Avascular Necrosis (AVN)

While Avascular Necrosis (AVN) might not be a household term, it’s a condition that can significantly impact your health, particularly in your bones and joints. Just like with many health issues, catching AVN early is key.

If we detect it early, we have a better chance of stopping it from causing severe damage to our bones and joints. You must know what it is, what causes it, and what you can do to stay as healthy as possible. Education is the first step in taking control of your health, and that’s what we’re here to do!

What is Avascular Necrosis?

Avascular Necrosis, often abbreviated as AVN, is a medical condition you might also hear referred to as Osteonecrosis. But what does this mouthful of a term mean?

At its core, AVN/Osteonecrosis is all about the health of your bones and, more specifically, what happens when that health gets compromised. You see, bones are living tissues, and just like any other part of our body, they need a good supply of blood to stay alive and function correctly.

AVN is a condition where the blood supply to a particular bone is disrupted, leading to a cascade of problems we’ll get into shortly.

Causes of Avascular Necrosis

Common Risk Factors

1. Trauma and Injury

One of the more common culprits behind Avascular Necrosis is trauma or injury to a bone. When a bone is fractured or dislocated, it can disrupt the blood supply to that area. This interruption in blood flow can set the stage for AVN to develop.

2. Chronic Steroid Use

While valuable for various medical conditions, steroids can have side effects when used for prolonged periods. One of these side effects is the potential to affect the blood supply to the bones. Chronic steroid use, whether for autoimmune diseases or other conditions, can increase the risk of AVN.

3. Alcohol Abuse

Excessive alcohol consumption can harm not only your liver but also your bones. It can directly impact blood vessels, decreasing blood flow to the bones. Over time, this can contribute to AVN, especially in the hip.

4. Certain medical conditions (e.g., sickle cell disease)

Some medical conditions, like sickle cell disease, can lead to abnormal red blood cells that struggle to flow through blood vessels. This can result in blockages in the small blood vessels supplying bones, making individuals with such conditions more susceptible to AVN.

Less Common Risk Factors

1. Radiation Therapy

Radiation therapy is a vital cancer treatment, but it can have unintended consequences. In some cases, radiation therapy near a bone can damage blood vessels, impairing blood supply and potentially triggering AVN.

2. Blood clotting disorders

Disorders that affect blood clotting can increase the risk of clot formation within blood vessels. If a clot obstructs blood flow to a bone, it can initiate the development of AVN.

Symptoms and Diagnosis of Avascular Necrosis

Early Signs and Symptoms of AVN

1. Joint Pain

The early stages of Avascular Necrosis often go unnoticed, but one of the telltale signs is joint pain. This pain can be persistent, deep, and may start gradually. Initially, it might be mild and intermittent, often mistaken for common aches. However, the pain can become more intense and persistent as AVN progresses.

2. Limited Range of Motion

AVN affects the bone’s structural integrity and can limit your joint’s range of motion. Moving your affected joint as freely as before may be difficult. Simple actions like bending a knee or raising an arm can become challenging and uncomfortable.

How AVN Progresses

Understanding how AVN progresses is crucial because it can help you gauge the severity of the condition and the urgency of seeking treatment. As the blood supply continues to be compromised, the bone tissue begins to break down.

This process can lead to small fractures and the eventual collapse of the bone. In essence, untreated AVN can escalate from minor discomfort to debilitating joint damage, significantly impacting your quality of life.

Diagnostic Methods

1. X-Rays

X-rays are often the first line of diagnostic imaging for AVN. They can reveal changes in bone structure, including areas of bone damage and collapse. However, X-rays may only sometimes detect AVN in its very early stages.

2. MRI Scans

Magnetic Resonance Imaging (MRI) scans are highly effective in detecting AVN, even in its early stages. MRI provides detailed images of bone and soft tissue, allowing healthcare professionals to assess the extent of bone damage and plan appropriate treatment.

3. Bone Scans

Bone scans involve injecting a small amount of radioactive material into your bloodstream. This material accumulates in areas of increased bone activity, which can help identify regions affected by AVN. Bone scans are especially useful for detecting AVN in its early stages.

Common Sites of Avascular Necrosis

Avascular Necrosis (AVN) can affect various body parts, but there are specific joints where it tends to strike more frequently. Let’s take a closer look at these common sites:

Hip Joint AVN

The hip joint is one of the most common areas affected by AVN. Hip AVN can cause severe pain in the groin or buttocks, making walking, standing, or even sitting comfortably difficult. If left untreated, it can lead to hip joint collapse, which may necessitate total hip replacement surgery.

Knee Joint AVN

AVN in the knee joint can result in pain and difficulty with knee movement. Individuals with knee AVN may experience discomfort while walking or bending their knees. It can lead to significant joint damage in advanced cases and may require surgical intervention.

Shoulder Joint AVN

Although less common than hip or knee AVN, the shoulder joint can also be affected. Symptoms may include pain when lifting or moving the arm, which can lead to joint dysfunction over time. Treatment options for shoulder AVN may include medications, physical therapy, or, in severe cases, surgery.

Other Affected Areas

It’s important to note that AVN can affect any bone in the body, though it’s less common in certain areas. Some other bones and joints that AVN can impact include: 

  • Ankle joint: AVN in the ankle can lead to pain and difficulty walking.
  •  Wrist joint: AVN in the wrist can cause discomfort and reduced hand function. 
  • Elbow joint: AVN in the elbow can result in pain and limited arm movement. 
  • Jawbone: AVN in the jawbone can lead to jaw pain and difficulties with chewing.
While AVN in these less common sites is rarer, it can still cause significant discomfort and functional limitations. Prompt diagnosis and appropriate treatment are crucial, regardless of the affected area.
Understanding where AVN tends to strike can help individuals and healthcare professionals be vigilant for symptoms in these specific joints. Early detection and intervention remain key factors in managing AVN effectively. In the next section, we’ll explore the various treatment options available for individuals diagnosed with Avascular Necrosis.

Treatment Options for Avascular Necrosis

Regarding managing Avascular Necrosis (AVN), several approaches are available, each tailored to the severity of the condition and the affected joint. Let’s explore these treatment options in detail:

Non-surgical Approaches

1. Medications For Pain Management

Pain relief is a crucial aspect of AVN treatment. Over-the-counter pain relievers or prescription medications can help manage the discomfort associated with AVN. In some cases, medications may also include drugs to slow the progression of AVN by improving blood flow to the affected bone.

2. Physical Therapy

Physical therapy plays a pivotal role in AVN management. A physical therapist can design a customised exercise program to improve joint function, strengthen muscles, and reduce pain. These exercises help maintain joint mobility and reduce the risk of complications.

Surgical Interventions

1. Core Decompression

Core decompression is a surgical procedure primarily used in the early stages of AVN, especially for hip joint AVN. It involves drilling a hole into the affected bone to relieve pressure and stimulate the formation of new blood vessels. This could slow down or stop the progression of AVN.

2. Bone Grafting

In cases where AVN has already caused significant bone damage, bone grafting may be necessary. During this procedure, healthy bone tissue is transplanted from one part of the body (or a donor) to the affected area. This helps to strengthen the bone and promote healing.

3. Total Joint Replacement

Total joint replacement is considered when AVN has led to severe joint damage and pain that can’t be managed through other methods. In this procedure, the damaged joint is removed and replaced with an artificial joint (prosthesis). Total joint replacement can significantly improve joint function and reduce pain.

Choosing the Right Treatment Plan

Selecting the most suitable treatment plan depends on various factors, including the severity of AVN, the affected joint, and the individual’s overall health. Your healthcare provider will work closely with you to assess your condition and help you make informed decisions about which treatment approach is best for you.

Rehabilitation and Recovery

After any surgical procedure or as part of non-surgical treatment, rehabilitation is a crucial phase. Physical therapy and exercises will be recommended to help you regain strength and mobility in the affected joint. The duration of rehabilitation and recovery can vary depending on the treatment chosen and the individual’s response.
Remember, early intervention and a proactive approach to managing AVN can yield the best outcomes. If you or someone you know is dealing with AVN symptoms, consulting with an orthopaedic specialist is a crucial first step in developing an effective treatment plan.
In the next section, we’ll explore some lifestyle changes and preventive measures that can help reduce the risk of developing Avascular Necrosis and support long-term joint health.

Lifestyle Changes and Prevention of Avascular Necrosis (AVN)

Avascular Necrosis can be a challenging condition, but there are steps you can take to manage it and reduce the risk of developing it. Let’s delve into some lifestyle changes and preventive measures:

Lifestyle Modifications for AVN Patients

1. Weight Management

Maintaining a healthy weight is crucial for AVN patients, especially for those with weight-bearing joint involvement like the hips and knees. Excess body weight can place added stress on already compromised joints, exacerbating pain and further damaging the affected area. Consult with your healthcare provider to establish a weight management plan tailored to your needs.

1. Weight Management

Maintaining a healthy weight is crucial for AVN patients, especially for those with weight-bearing joint involvement like the hips and knees. Excess body weight can place added stress on already compromised joints, exacerbating pain and further damaging the affected area. Consult with your healthcare provider to establish a weight management plan tailored to your needs.

2. Limiting Alcohol and Tobacco Use

If you’re dealing with AVN, it’s essential to limit or, ideally, abstain from alcohol and tobacco. Both alcohol and smoking can adversely affect blood circulation, which is already compromised in AVN. These substances can exacerbate the condition and hinder your body’s natural healing processes.

3. Exercise and Joint-Friendly Activities

While rest is essential during AVN treatment and recovery, physical activity remains crucial. Consult with a physical therapist to develop an exercise program tailored to your condition. These exercises can help maintain joint mobility, strengthen supporting muscles, and improve overall joint health. Opt for low-impact activities like swimming or cycling, which put less stress on your affected joints.

Prevention Strategies for Those at Risk

1. Early Treatment of Underlying Conditions

If you have medical conditions known to increase the risk of AVN, such as sickle cell disease or certain clotting disorders, it’s crucial to manage these conditions effectively. Follow your healthcare provider’s recommendations, adhere to prescribed treatments, and attend regular check-ups to catch any potential complications early.

2. Avoiding Excessive Steroid Use

If you’re prescribed steroids for any medical condition, use them only as directed by your healthcare provider. Avoid prolonged or excessive steroid use, as this can increase the risk of AVN. If you have concerns about your medication regimen, discuss them with your healthcare provider to explore alternative treatments or strategies.

3. Injury Prevention

Trauma and injuries can trigger AVN, so preventing accidents is essential. Wear appropriate safety gear during sports and physical activities, and be cautious in environments where falls or accidents are more likely. Falls can cause fractures and damage blood vessels, potentially leading to AVN in the affected area.

By implementing these lifestyle changes and prevention strategies, you can actively manage your AVN or reduce your risk if you’re in a high-risk category. Remember, early intervention and proactive measures can significantly affect your bone and joint health.
Knowledge is your ally when it comes to health. By staying informed, proactively managing your risk factors, and seeking timely medical care, you can navigate the challenges posed by Avascular Necrosis and maintain the health and mobility of your precious joints. Your joint health is worth the effort, so don’t hesitate to take that first step towards a healthier, pain-free future.

Dr Lee is an experienced orthopaedic surgeon who specializes in

Avascular Necrosis (AVN)

He will assess your condition and advise the best form of treatment for your condition. With proper treatment, patients can look forward to a full and quick recovery without complications.

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Dr Lee Eu Jin - Orthopaedic Doctor - Liberty Orthopaedic Clinic

Dr Lee Eu Jin

  • CONSULTANT ORTHOPAEDIC SURGEON
  • JOINT REPLACEMENT SPECIALIST AND SPORTS SURGEON

MBBS (London), MRCS (Edin),
M.Med (Orth), FRCS (Orth & Trauma)

Dr Lee Eu Jin is a Consultant Orthopaedic Surgeon with a subspecialty interest in hip and knee surgery.